Data Model Manual

HAWK’s data model is designed to accommodate wildlife, arthropod, and environmental health data from various sources, including local to national wildlife health surveillance systems, research initiatives, citizen-science based projects, or any other source of wildlife health information. We strongly recommend first learning about the core components of the data model: Project to Results, and Interpretation.

HAWK structures surveillance data following a hierarchy, capturing relevant epidemiological information at each step. The full hierarchy includes:

  1. Project: A planned set surveillance operations with specific goals or a common topic, usually with a defined scope and set of tasks with a common leader and organizer (e.g., a national wildlife health surveillance system).
  2. Surveillance Activity: Specific surveillance goal and methodology (who, where, when, what, why, how) documented following a standard metadata format.
  3. Field Visit: A recorded interval during which fieldwork or data collection are conducted.
  4. Location: Areas where activities are conducted.
  5. Area Effort, Track Effort, and Point Effort: Units of effort associated with the collection of Events (see below) in a determined area (e.g., Events in a sector within protected area) along in a linear feature (e.g., Events in transect or ranger patrol track), or at spatial point (e.g., a set of mist nests placed during a specific period of time for a sampling Event), respectively.
  6. Event: Point epidemiological unit with a spatiotemporal coordinate (longitude and latitude) where wildlife health surveillance data are collected from.
  7. Source: An observed, diagnosed, or sampled entity to assess their health status or health hazard presence. There are four Source types:​
    • Group: more than one individual of the same taxa
    • Animal: one individual
    • Environmental: a site where measurements on environmental properties are made or samples are collected from (e.g., ponds or feces in the field)
    • Arthropod: the population of arthropods at a site
  8. Source Record: A record of a Source at a specific time t.
  9. Specimen: A sample taken from a Source.
  10. Diagnostic: A test conducted on a Source or collected Specimen to assess health metrics.
  11. Result: The outcome of a Diagnostic for a specific health metric and the corresponding interpretation.
  12. Interpretation: The final status assigned to a Specimen or Source Record following documented case definitions.

The main relationships among the basic units of the data model are shown in Figure 1 below:

Figure 1: Basic relationships among the basic units of the data model.

HAWK employs a modular approach to the data model, enabling components to be added based on specific user needs.

NoteCase Study 1

When data comes from wildlife mortality reported by a community member through a mobile application:

The Surveillance Activity contains a description of the methodology

The Field Visit could be a day when the mortality was found

The Location could be the site where the mortality was found

An Event is the epidemiological unit with latitude, longitude, and time representing the position where dead animals were found

The Animal Source Records describe the dead animals

No Specimens, Diagnostics, or Results data are generated

No Effort is involved as the animals are found opportunistically

Figure Case Study 1: An illustration of how case study 1 data is structured in the data model.

This flexible structure means the model remains efficient and scalable, adapting to different users and surveillance needs.

Main Units of the Data Model

Project

A Project in the data model represents a planned set surveillance operations with specific goals or a common topic, usually with a defined scope and set of tasks with a common leader and organizer (e.g., a national wildlife health surveillance system) supported by specific entities and lead by specific individuals.

Projects serve as the first hierarchical unit in the database under an Organization and must contain at least one Surveillance Activity. They can be time-limited, spanning a single date, or ongoing for an extended period as needed.

Key properties of a Project include:

  • Project ID
  • Project Code
  • Project Cross-Reference ID
  • Project Cross-Reference Origin
  • Project Leader
  • Project Funding Sources

Other attributes are provided in the Data Dictionary (under construction)

NoteExample

Surveillance of New World Screwworm. The Project includes surveillance of adult flies trapped with baited devices, news sources reporting infestation cases in wildlife, and camera trap videos with wildlife showing wounds compatible with New World Screwworm infestation.

Surveillance Activity

Figure 2: Postition of Surveillance Activity in the data model.

A Surveillance Activity in the data model refers to a coordinated set of activities aimed at detecting diseases, demonstrating disease freedom, measuring incidence or prevalence, or assessing trends in specific health metrics within defined populations. In general, a Surveillance Activity will be characterized by a specific objective, and corresponding methods.

Each Surveillance Activity includes metadata describing objectives and methods. Key properties of a Surveillance Activity include:

  • Targeted species, populations, and hazards
  • Samples and collection methods
  • Diagnostics conducted and case definitions
  • Start and End Dates
  • Biological, Chemical, Physical, and Physiological targets
  • Taxa included
  • Involved partners
  • Definitions of Locations, Events, and Sources
  • Source identification, Specimens, and Effort methods
  • Diagnostic techniques and case definitions

Other attributes are provided in the Data Dictionary (under construction)

A Surveillance Activity can span multiple Field Visits, Locations, and Source types (e.g., Groups, Animals, Environmental and Arthropod Sources).

NoteCase Study 2

The longitudinal assessment of coronavirus shedding in two Eidolon helvum bat roosts in Africa aimed understanding the patterns of coronavirus shedding through their reproductive cycle assessing common patterns in two roost separated by thousands of kilometers where the reproductive season do not match over time. The methods involved collecting a fixed number of fecal samples from the two bat roosts of the same species every month for 12 months, with subsequent testing for Coronaviridae sp. The Project in this case was USAID PREDICT and this study was a specific Surveillance Activity. Field Visits were each visit monthly to the roosts, the Locations were the two roosts, the Source Records were the bats at the sampling date each month, and the Specimens are the fecal samples taken from the roost

NoteOutbreak Investigation

Each outbreak investigation is considered a Surveillance Activity. An Outbreak Surveillance Activity can encompass the initial Field Visit that led to the outbreak detection and subsequent Field Visits associated with the investigation and control. The initial Field Visit that led to the outbreak detection may have already been part of another Surveillance Activity and also the Outbreak Surveillance Activity (e.g., routine monitoring of a particular area), and this relationship is maintained to allow traceability on the history of detections.

For instance, an outbreak may first be detected during routine patrols by rangers. In such cases, the initial ranger-conducted Field Visit and its components should belong to both the ranger patrol Surveillance Activity and also the outbreak Surveillance Activity. Follow-up Field Visits (e.g., by veterinarians or public health officers investigating the outbreak) should be assigned exclusively to the outbreak Surveillance Activity.

Field Visit

Figure 3: Position of Field Visit in the data model.

A Field Visit in the data model represents a defined time period—including a start and end date—during which Locations are visited, Events and Sources are conducted, identified, or observed, and Specimens might be collected and documented. The length of a Field Visit is flexible. The meaning of a Field Visit depends on the methodology of the Surveillance Activity. Users must define what a Field Visit represents and document it in the Surveillance Activity metadata.

Key properties of a Field Visit include:

  • Start and End Date
  • Field Visit ID and Code
  • Field Visit Cross-Reference ID and Origin
  • Field Visit Leader

Other attributes are provided in the Data Dictionary (under construction)

NoteCase Study 3

In the monitoring of wildlife anomalies through camera traps (for example, as described here), a Field Visit refers to the period during which a set of camera traps was deployed in the field

Location

Figure 4: Position of Location in the data model.

In the data model, a Location represents a general area where Field Visits take place. Locations are not defined by exact latitude and longitude coordinates (unlike Events, defined later), but they serve as a broader spatial grouping for organizing data. The meaning of a Location depends on the methodology of the Surveillance Activity. Users must define what a Location represents and document it in the Surveillance Activity metadata.

Key attributes of a Location include:

  • Location ID and Code
  • Location Cross-Reference ID and Origin
  • Location Type

Other attributes are provided in the Data Dictionary (under construction)

NoteCase Study 4

In the sampling of wildlife in markets, a Location can refer to a specific market

Effort

In the data model, Effort contains the information associated with the spatial and temporal metrics used to activel obtain Sources in the field.

When Source Records are not linked to an Effort (e.g., opportunist finding of dead animals), then no Effort is involved.

Figure 5: Position of Effort in the data model.

Area Effort

Area Effort refers to the spatial and temporal work to find or document Events within an area (e.g., square kilometers explored in x amount of time) within a Location. The meaning of Area Effort depends on the methodology of the Surveillance Activity. Users must define what a Area Effort represents and document it in the Surveillance Activity metadata.

Key attributes of a Area Effort include:

  • The spatial effort unit (e.g., square meters)
  • The spatial effort (e.g., 100)
  • The temporal effort unit (e.g., hours)
  • The temporal effort (e.g., 6)
  • The spatial coordinates of the area

Other attributes are provided in the Data Dictionary (under construction)

NoteCase Study 5

Following recommendations here, in an outbreak investigation, dead marine birds are actively searched in a beach. In this case, the beach is the Location and each area explored within the beach during a specific period of time represents an Area Effort

Track Effort

A Track Effort refers to the spatial and temporal work to find or document Events in linear features (e.g., kilometers walked through a set of spatial coordinates in an x period of time) within a Location. The meaning of a Track Effort depends on the methodology of the Surveillance Activity. Users must define what a Track Effort represents and document it in the Surveillance Activity metadata.

Key attributes of a Track Effort include:

  • The spatial effort unit (e.g., kilometers)
  • The spatial effort (e.g., 15)
  • The temporal effort unit (e.g., hours)
  • The temporal effort (e.g., 6)
  • The spatial coordinates of the track

Other attributes are provided in the Data Dictionary (under construction)

NoteCase Study 6

Following the ranger-based wildlife morbidity and mortality surveillance described here, a sector within a protected area is the Location and the route traveled by patrolling rangers to find wildlife morbidity and mortality during a specific period of time represents a Track Effort.

Track Efforts are not nested in Areas Efforts. If a methodology involves Events nested in Track Efforts nested in Area Efforts then, the link between both types of Effort can be made through the spatial data and through Tags (see “Advanced”).

Point Effort

A Point Effort refers to the spatial and temporal work to find or document Events at a specific spatio-temporal coordinate (e.g., a device set up at a specific longitude and latitud for x amount of time to capture mosquitoes) within a Location. The meaning of a Point Effort depends on the methodology of the Surveillance Activity. Users must define what a Point Effort represents and document it in the Surveillance Activity metadata.

Key attributes of a Point Effort include:

  • The spatial effort unit (e.g., mist net)
  • The spatial effort (e.g., 1)
  • The spatial coordinates (longitud and latitude)
  • The temporal effort unit (e.g., hours)
  • The temporal effort (e.g., 2)

Other attributes are provided in the Data Dictionary (under construction)

NoteCase Study 7

In the counting of dead birds at a wetland from a tower and using binoculars, the Point Collection is the position and number of observers recording dead birds from the tower during a specific period of time

NoteCase Study 8

In the monitoring of wildlife morbidity through camera traps, the Point Collection is the number camera traps deployed at a specific position to photograph animals and the hours or days active.

Area, Track and Point Effort fields also help capture issues encountered when searching for Sources, such as camera traps running out of power, being stolen, or damaged mist nets.

Efforts can contain between zero (e.g., an unsuccessful capture where no animals are caught) and an unlimited number of Source Records**.

Event

Figure 6: Position of Event in the data model.

In the data model, an Event represents a distinct spatio-temporal coordinate where Source Record data is collected from (e.g., specific longitude, latitude, and timestamp). The definition of Event depends on the methodology of the Surveillance Activity. Users must define what an Event represents and document it in the Surveillance Activity metadata. We strongly recommend that an Event represents the minimal epidemiological unit of interest containing Source Records at position p and time t (e.g., the sampling event of animals in a cage, the collection of mosquitoes using a trap, the position of a dead animal found in the field at time t)

Key attributes of a Event include:

  • Start Date
  • Event ID
  • Event Code
  • Event Cross-Reference ID
  • Event Cross-Reference Origin
  • Longitude & Latitude
  • Coordinate Reference System (CRS) used

Other attributes are provided in the Data Dictionary (under construction)

NoteCase Study 9

A pair of mist nets are deployed to capture bats and sample them. The Event in this case is the sampling of the bats captured at time t using the mist nets. The nets are part of a Point Effort. In this case, the Event receives the same spatial coordinates as the Point Effort

NoteCase Study 10

A dead animal is found during a ranger patrol. In this case the Event is the position of the dead animal and the time of encounter

NoteCase Study 11

Injured animals are recorded using a camera trap. In this case the Event is each capture of animals by the camera trap and they receive the same spatial coordinates as the Point Effort. The Point Effort is the camera traps at a specific spatial position and the deployment time

For more examples see here

Other relevant characteristics of an Event include:

An Event might not belong to a Area, Track, or Point Effort. For example, the position of dead birds accidentally found in a beach or sampling of the animals in cages in a wet market.

An Event can include more than one Source type (see next section for a full description of Sources). For example, mosquito traps and collection of wastewater at the same position p and time t.

An Event can include or not at-observation normal (“healthy”) animals depending on the definition of Event.

An Event might not contain any Source Records (see next section for a full description of Sources). For example, when a mist net is deployed but it fails to capture any animal. The mist net (Point Effort is deployed, the sampling Event is conducted at time t but no animal is captured).

Source and Source Records

Figure 8: Position of Source Records in the data model.

General Overview

In the data model, a Source is an epidemiological unit of interest that can be observed, necropsied, diagnosed, or provide Specimens for analysis. The data model manages four types of Sources: i) a group of individuals of the same taxa (Group Source), ii) individual animal (Animal Source), iii) a site providing arthropods (Arthropod Source), and iv) a site providing environmental abiotic specimens (e.g., wastewater) or biotic specimens (e.g., feces not linked to a specific animal) or where metrics such are pH can be measured at (Environmental Source).

Identified Sources can be found at position p and time t in a single or multiple Events.

Group Source

A Group Source is a unit of individuals of the same taxa that belong to a common entity, such as a herd, roost, area, site, farm, cage, stall, or enclosure, forming a single epidemiological unit. Group Sources can be observed, captured, diagnosed, and interpreted as a full unit, and provide collective Specimens if sampling is conducted. A Group Source can be shipped and stored when the individuals are dead.

Figure 9: Detailed relationships of Group Source in the data model.

Group Source Record

A Group Source Record documents the animals of a Group Source at time t, categorized by sex, age, and life status (e.g., live or dead).

Key attributes of a Group Source Record include time independent variables:

  • Group Source ID
  • Record number
  • Observed anomalies
  • Potential causes of anomalies
  • Potential causes of death

Other attributes are provided in the Data Dictionary (under construction)

Several attributes are recorded at the group level and, therefore, multiple options can be included. For example, several observed anomalies may be listed for a Group Source Record, but their distribution across individuals cannot be recorded.

A Group Source Record can be used for a Diagnostic (e.g., assessing the body condition of a specific herd using a standardized metric).

Carcasses of a Group Source Record can be recorded collectively (e.g., multiple dead frogs in a plastic bag) and they can be stored, shipped, and used collectively in a diagnostic test (see “Storage”, “Shipments”, and “Diagnostic” below).

Carcasses of a Group Source Record cannot have a collective necropsy. The individuals animals must be converted to Animal Sources.

The total number of animals of a specific taxon in an Event is the sum of the individuals of the taxa in the Group Source Record and each individual animal of the same taxa recorded as Animal Source Record. For example, consider a herd of 20 cows illegally raised in a protected area whose health is assessed at time t. If two cows are sampled, the two sampled cows should be documented as two separate Animal Source Records (one per cow), while the remaining 18 cows are recorded as a single Group Source Record, categorized by sex, age, and life status. In this scenario, the total number of cows is 20—the 18 recorded in the Group Source Record plus the two documented as Animal Source Records. The “herd” identity of these 20 cows split in three Source Records can be maintained using tags (see Complexities). If, however, the Group Source Record incorrectly includes all 20 cows while two of them are also recorded as Animal Source Record, the total count would incorrectly sum to 22.

Animal Source

An Animal Source represents a single individual. Animal Sources can be observed, captured, tested, necropsied, interpreted, and provide Specimens directly or during a Necropsy. An Animal Source can be shipped and stored if the individual is dead.

Figure 10: Detailed relationships of Animal Source in the data model.

Animal Source Record

An Animal Source Record represents an individual Animal Source at time t.

Key attributes of a Animal Source Record include:

  • Animal source ID
  • Record number
  • Species
  • Sex
  • Age
  • Life status
  • Observed anomalies
  • Potential causes of anomalies or death

Other attributes are provided in the Data Dictionary (under construction)

Some properties of an Animal Source Record allow single or multiple selections. For instance, an animal’s life status is recorded as one category (e.g., “live” or “dead”), whereas multiple anomalies may be reported for the same individual at time t (e.g., wounds, hair loss, diarrhea).

An Animal Source Record can be categorized as dead or live at time t. A live animal at time t can be part of an Event, depending on the Event’s definition.

An Animal Source Record can be used directly for a Diagnostic (e.g., performing X-rays on an animal).

Vaccinations administered to an Animal Source Record can be added ensuring that vaccination history accumulates.

The carcass of an Animal Source Record can be stored, shipped, and used in a diagnostic test (see “Storage”, “Shipments”, and “Diagnostic” below). Live Animal Sources cannot can be shipped or stored.

The carcass of an Animal Source Record can be used in a Necropsy (see “Necropsy” below).

The total number of animals of a specific taxon in an Event is the sum of the individuals of the taxa in the Group Source Record and each individual animal of the same taxa recorded as Animal Source Record. For example, consider a herd of 20 cows illegally raised in a protected area whose health is assessed at time t. If two cows are sampled, the two sampled cows should be documented as two separate Animal Source Records (one per cow), while the remaining 18 cows are recorded as a single Group Source Record, categorized by sex, age, and health status. In this scenario, the total number of cows is 20—the 18 recorded in the Group Source Record plus the two documented as Animal Source Records. The “herd” identity of these 20 cows split in three Source Records can be maintained using a cluster (see Complexities). If, however, the Group Source Record incorrectly includes all 20 cows while two of them are also recorded as Animal Source Record, the total count would incorrectly sum to 22.

Necropsy

A Necropsy is linked to a specific Animal Source Record. A Necropsy can take place in the field or in a facility.

Key attributes of a Necropsy include:

  • Necropsy Identifier
  • Necropsy Cross Reference Identifier
  • Necropsy Date
  • Findings per system

Other attributes are provided in the Data Dictionary (under construction)

The Necropsy findings are reported through text in fields such as “Gastrointestinal System”, “Reproductive System”, etc. The list of anatomical components encompassed by each of these elements or systems is provided in the table below and they follow the National Agricultural Library Thesaurus Concept Space (NALT), a controlled vocabulary of terms related to agricultural, biological, physical and social sciences (https://lod.nal.usda.gov/nalt/en/).

Eyes/Eyelids
Topography NALT_URI Definition_NALT Alternative_name
retina https://lod.nal.usda.gov/nalt/38995 The ten-layered nervous tissue membrane of the eye. It is continuous with the optic nerve and receives images of external objects and transmits visual impulses to the brain. Its outer surface is in contact with the choroid and the inner surface with the vitreous body. The outer-most layer is pigmented, whereas the inner nine layers are transparent. NA
eye lens https://lod.nal.usda.gov/nalt/38989 NA
sclera https://lod.nal.usda.gov/nalt/290574 The white, opaque, fibrous, outer tunic of the eyeball, covering it entirely excepting the segment covered anteriorly by the cornea. It is essentially avascular but contains apertures for vessels, lymphatics, and nerves. It receives the tendons of insertion of the extraocular muscles and at the corneoscleral junction contains the canal of Schlemm. eye white
eyes https://lod.nal.usda.gov/nalt/28392 eye
lacrimal apparatus https://lod.nal.usda.gov/nalt/28564 lacrimal gland
lacrimal apparatus https://lod.nal.usda.gov/nalt/28564 conjunctival sac
iris (eyes) https://lod.nal.usda.gov/nalt/38993 The most anterior portion of the uveal layer, separating the anterior chamber from the posterior. It consists of two layers - the stroma and the pigmented epithelium. Color of the iris depends on the amount of melanin in the stroma on reflection from the pigmented epithelium. NA
conjunctiva https://lod.nal.usda.gov/nalt/28561 NA
cornea https://lod.nal.usda.gov/nalt/29206 NA
eyelids https://lod.nal.usda.gov/nalt/38991 NA
External Ear/Middle Ear/Inner Ear
Topography NALT_URI Definition_NALT Alternative_name
inner ear https://lod.nal.usda.gov/nalt/332326 The essential part of the hearing organ consists of two labyrinthine compartments: the bony labyrinthine and the membranous labyrinth. The bony labyrinth is a complex of three interconnecting cavities or spaces (Cochlea; vestibular labyrinth; and semicircular canals) in the temporal bone. Within the bony labyrinth lies the membranous labyrinth which is a complex of sacs and tubules (cochlear duct; saccule and utricle; and semicircular ducts) forming a continuous space enclosed by epithelium and connective tissue. These spaces are filled with labyrinthine fluids of various compositions. labyrinth (inner ear)
guttural pouch https://lod.nal.usda.gov/nalt/35107 NA
ears https://lod.nal.usda.gov/nalt/35074 ear
middle ear https://lod.nal.usda.gov/nalt/332330 The space and structures directly internal to the tympanic membrane and external to the inner ear (labyrinth). Its major components include the auditory ossicles and the eustachian tube that connects the cavity of middle ear (tympanic cavity) to the upper part of the throat. tympanum
middle ear https://lod.nal.usda.gov/nalt/332330 The space and structures directly internal to the tympanic membrane and external to the inner ear (labyrinth). Its major components include the auditory ossicles and the eustachian tube that connects the cavity of middle ear (tympanic cavity) to the upper part of the throat. tympanic cavity
otoliths https://lod.nal.usda.gov/nalt/191711 Structures of the inner ear which function in orientation and equilibrium sensing of vertebrates. Otoliths contain calcium concretions useful for species identification and age determination of fish, and provide information about their life history and ecology. otoconia
otoliths https://lod.nal.usda.gov/nalt/191711 Structures of the inner ear which function in orientation and equilibrium sensing of vertebrates. Otoliths contain calcium concretions useful for species identification and age determination of fish, and provide information about their life history and ecology. otolithic membrane
otoliths https://lod.nal.usda.gov/nalt/191711 Structures of the inner ear which function in orientation and equilibrium sensing of vertebrates. Otoliths contain calcium concretions useful for species identification and age determination of fish, and provide information about their life history and ecology. statoconia
otoliths https://lod.nal.usda.gov/nalt/191711 Structures of the inner ear which function in orientation and equilibrium sensing of vertebrates. Otoliths contain calcium concretions useful for species identification and age determination of fish, and provide information about their life history and ecology. otolites
ear canal https://lod.nal.usda.gov/nalt/339897 The narrow passage way that conducts the sound collected by the ear auricle to the tympanic membrane. auditory canal
ear canal https://lod.nal.usda.gov/nalt/339897 The narrow passage way that conducts the sound collected by the ear auricle to the tympanic membrane. meatus acusticus externus
Nose/Nostrils/Nasal cavity/Vomeronasal organ
Topography NALT_URI Definition_NALT Alternative_name
nose https://lod.nal.usda.gov/nalt/54351 nostrils
vomeronasal organ https://lod.nal.usda.gov/nalt/308291 An accessory chemoreceptor organ that is separated from the main olfactory mucosa. It is situated at the base of nasal septum close to the vomer and nasal bones. It forwards chemical signals (such as pheromones) to the central nervous system, thus influencing reproductive and social behavior. In humans, most of its structures except the vomeronasal duct undergo regression after birth. Jacobson organ
vomeronasal organ https://lod.nal.usda.gov/nalt/308291 An accessory chemoreceptor organ that is separated from the main olfactory mucosa. It is situated at the base of nasal septum close to the vomer and nasal bones. It forwards chemical signals (such as pheromones) to the central nervous system, thus influencing reproductive and social behavior. In humans, most of its structures except the vomeronasal duct undergo regression after birth. Jacobson's organ
vomeronasal organ https://lod.nal.usda.gov/nalt/308291 An accessory chemoreceptor organ that is separated from the main olfactory mucosa. It is situated at the base of nasal septum close to the vomer and nasal bones. It forwards chemical signals (such as pheromones) to the central nervous system, thus influencing reproductive and social behavior. In humans, most of its structures except the vomeronasal duct undergo regression after birth. vomeronasal nerve
nasal mucosa https://lod.nal.usda.gov/nalt/53591 NA
nasal cavity https://lod.nal.usda.gov/nalt/54350 NA
Mouth/Beak/Tongue/Teeth/Palate
Topography NALT_URI Definition_NALT Alternative_name
teeth https://lod.nal.usda.gov/nalt/32369 dentine
teeth https://lod.nal.usda.gov/nalt/32369 dentition
beak https://lod.nal.usda.gov/nalt/16134 NA
gingiva https://lod.nal.usda.gov/nalt/9531 Oral tissue surrounding and attached to teeth. interdental papilla
gingiva https://lod.nal.usda.gov/nalt/9531 Oral tissue surrounding and attached to teeth. gums (mouth)
lips https://lod.nal.usda.gov/nalt/50308 NA
salivary glands https://lod.nal.usda.gov/nalt/2899 NA
palate https://lod.nal.usda.gov/nalt/26789 roof of the mouth
palate https://lod.nal.usda.gov/nalt/26789 hard palate
palate https://lod.nal.usda.gov/nalt/26789 soft palate
mouth https://lod.nal.usda.gov/nalt/33560 buccal cavity
mouth https://lod.nal.usda.gov/nalt/33560 oral cavity
mouth https://lod.nal.usda.gov/nalt/33560 periodontium
tongue https://lod.nal.usda.gov/nalt/53559 NA
Skin/Integument/Exoskeleton
Topography NALT_URI Definition_NALT Alternative_name
Insect cuticle https://lod.nal.usda.gov/nalt/9104 NA NA
Perineum https://lod.nal.usda.gov/nalt/57466 NA NA
Scar NA NA NA
Scent glands https://lod.nal.usda.gov/nalt/59050 NA Poll glands
Sebaceous glands https://lod.nal.usda.gov/nalt/38913 NA Tarsal glands
Skin (animal) https://lod.nal.usda.gov/nalt/32499 NA NA
Sweat glands https://lod.nal.usda.gov/nalt/38914 NA NA
Wounds and injuries https://lod.nal.usda.gov/nalt/728 NA NA
Antlers https://lod.nal.usda.gov/nalt/10565 NA NA
Claws https://lod.nal.usda.gov/nalt/26735 NA Talons
Claws https://lod.nal.usda.gov/nalt/26735 NA Nails (non-primates)
Claws https://lod.nal.usda.gov/nalt/26735 NA Claw horn
Comb (integument) https://lod.nal.usda.gov/nalt/28099 NA NA
Eyelashes NA NA NA
Feathers https://lod.nal.usda.gov/nalt/34442 NA NA
Fur https://lod.nal.usda.gov/nalt/27376 NA Coat (animal)
Hairs https://lod.nal.usda.gov/nalt/44301 NA Scalp hair
Hairs https://lod.nal.usda.gov/nalt/44301 NA Hairs (animal)
Hooves https://lod.nal.usda.gov/nalt/45820 NA Hoofs
Integument https://lod.nal.usda.gov/nalt/9103 NA Exuviae
Integument https://lod.nal.usda.gov/nalt/9103 NA Body wall
Nails (integument) https://lod.nal.usda.gov/nalt/47469 NA Nails (primates)
Nails (integument) https://lod.nal.usda.gov/nalt/47469 NA Nails (human)
Scales (integument) https://lod.nal.usda.gov/nalt/47470 NA NA
Wattles https://lod.nal.usda.gov/nalt/47472 NA NA
Subcutaneous Fat
Topography NALT_URI Definition_NALT Alternative_name
subcutaneous fat https://lod.nal.usda.gov/nalt/18338 NA
Musculoskeletal System
Topography NALT_URI Definition_NALT Alternative_name
joints (animal) https://lod.nal.usda.gov/nalt/36135 NA
tendons https://lod.nal.usda.gov/nalt/28572 Fibrous bands or cords of connective tissue at the ends of muscle fibers that serve to attach the muscles to bones and other structures. NA
bones https://lod.nal.usda.gov/nalt/18497 NA
skeletal muscle https://lod.nal.usda.gov/nalt/35050 NA
fascia https://lod.nal.usda.gov/nalt/28570 NA
skeleton https://lod.nal.usda.gov/nalt/53793 NA
Thoracic and Abdominal Cavities
Topography NALT_URI Definition_NALT Alternative_name
mediastinum https://lod.nal.usda.gov/nalt/51800 NA
body cavities https://lod.nal.usda.gov/nalt/1610 NA
abdominal cavity https://lod.nal.usda.gov/nalt/1609 NA
hemocoel https://lod.nal.usda.gov/nalt/18328 A body cavity of arthropods and some molluscs that contains blood or hemolymph, which functions as part of the circulatory system by directly bathing the organs. haemocoel
thoracic cavity https://lod.nal.usda.gov/nalt/18330 NA
Cardiovascular System
Topography NALT_URI Definition_NALT Alternative_name
Heart https://lod.nal.usda.gov/nalt/9341 NA Endocardium
Blood plasma https://lod.nal.usda.gov/nalt/18062 NA NA
Arteries https://lod.nal.usda.gov/nalt/10603 The vessels carrying blood away from the heart. NA
Inferior vena cava https://lod.nal.usda.gov/nalt/190442 The venous trunk which receives blood from the lower extremities and from the pelvic and abdominal organs. NA
Blood veins https://lod.nal.usda.gov/nalt/18176 NA NA
Blood vessels https://lod.nal.usda.gov/nalt/12438 NA NA
Jugular vein https://lod.nal.usda.gov/nalt/18177 NA NA
Coronary vessels https://lod.nal.usda.gov/nalt/12440 The veins and arteries of the heart. Coronary arteries
Coronary sinus https://lod.nal.usda.gov/nalt/190439 A short vein that collects about two thirds of the venous blood from the myocardium and drains into the right atrium. Coronary sinus, normally located between the left atrium and left ventricle on the posterior surface of the heart, can serve as an anatomical reference for cardiac procedures. NA
Hemolymph https://lod.nal.usda.gov/nalt/26359 Bloodlike fluid of the hemocoel in open circulatory systems of arthropods and most molluscs. Haemolymph
Portal vein https://lod.nal.usda.gov/nalt/18178 NA NA
Blood https://lod.nal.usda.gov/nalt/18059 NA NA
Iliac artery https://lod.nal.usda.gov/nalt/12442 NA NA
Hepatic artery https://lod.nal.usda.gov/nalt/12441 NA NA
Superior vena cava https://lod.nal.usda.gov/nalt/190443 The venous trunk which returns blood from the head, neck, upper extremities and chest. NA
Blood serum https://lod.nal.usda.gov/nalt/18139 The clear, watery portion of blood that separates out when blood coagulates. It lacks blood clotting factors such as fibrogen and prothrombin. Serum
Carotid arteries https://lod.nal.usda.gov/nalt/12439 NA NA
Caudal vein https://lod.nal.usda.gov/nalt/254549 NA Tail vein
Myocardium https://lod.nal.usda.gov/nalt/22397 The muscle tissue of the heart. It is composed of striated, involuntary muscle cells connected to form the contractile pump to generate blood flow. Cardiac muscle
Aorta https://lod.nal.usda.gov/nalt/10602 NA Aortic root
Thymocytes https://lod.nal.usda.gov/nalt/50929 NA NA
Fetal bovine serum https://lod.nal.usda.gov/nalt/191461 NA Fetal calf serum
Fetal bovine serum https://lod.nal.usda.gov/nalt/191461 NA Fbs (fetal bovine serum)
Pulmonary artery https://lod.nal.usda.gov/nalt/12444 NA NA
Umbilical arteries https://lod.nal.usda.gov/nalt/12445 NA NA
Saphenous vein https://lod.nal.usda.gov/nalt/18179 The vein which drains the foot and leg. NA
Ductus arteriosus https://lod.nal.usda.gov/nalt/28513 NA NA
Umbilical veins https://lod.nal.usda.gov/nalt/18180 NA NA
Heart atrium https://lod.nal.usda.gov/nalt/13743 NA NA
Vena cava https://lod.nal.usda.gov/nalt/18181 NA Venae cavae
Heart valves https://lod.nal.usda.gov/nalt/44757 NA NA
Heart ventricle https://lod.nal.usda.gov/nalt/44758 NA NA
Mesenteric arteries https://lod.nal.usda.gov/nalt/12443 NA NA
Respiratory System
Topography NALT_URI Definition_NALT Alternative_name
Lungs https://lod.nal.usda.gov/nalt/9345 NA NA
Larynx https://lod.nal.usda.gov/nalt/49283 NA NA
Spiracles https://lod.nal.usda.gov/nalt/61125 NA NA
Bronchi https://lod.nal.usda.gov/nalt/20020 The larger air passages of the lungs arising from the terminal bifurcation of the trachea. They include the largest two primary bronchi which branch out into secondary bronchi, and tertiary bronchi which extend into bronchioles and pulmonary alveoli. Secondary bronchi
Bronchi https://lod.nal.usda.gov/nalt/20020 The larger air passages of the lungs arising from the terminal bifurcation of the trachea. They include the largest two primary bronchi which branch out into secondary bronchi, and tertiary bronchi which extend into bronchioles and pulmonary alveoli. Primary bronchi
Bronchi https://lod.nal.usda.gov/nalt/20020 The larger air passages of the lungs arising from the terminal bifurcation of the trachea. They include the largest two primary bronchi which branch out into secondary bronchi, and tertiary bronchi which extend into bronchioles and pulmonary alveoli. Bronchus
Bronchi https://lod.nal.usda.gov/nalt/20020 The larger air passages of the lungs arising from the terminal bifurcation of the trachea. They include the largest two primary bronchi which branch out into secondary bronchi, and tertiary bronchi which extend into bronchioles and pulmonary alveoli. Tertiary bronchi
Air sacs https://lod.nal.usda.gov/nalt/5852 NA NA
Vomeronasal organ https://lod.nal.usda.gov/nalt/308291 An accessory chemoreceptor organ that is separated from the main olfactory mucosa. It is situated at the base of nasal septum close to the vomer and nasal bones. It forwards chemical signals (such as pheromones) to the central nervous system, thus influencing reproductive and social behavior. In humans, most of its structures except the vomeronasal duct undergo regression after birth. Jacobson organ
Vomeronasal organ https://lod.nal.usda.gov/nalt/308291 An accessory chemoreceptor organ that is separated from the main olfactory mucosa. It is situated at the base of nasal septum close to the vomer and nasal bones. It forwards chemical signals (such as pheromones) to the central nervous system, thus influencing reproductive and social behavior. In humans, most of its structures except the vomeronasal duct undergo regression after birth. Jacobson's organ
Vomeronasal organ https://lod.nal.usda.gov/nalt/308291 An accessory chemoreceptor organ that is separated from the main olfactory mucosa. It is situated at the base of nasal septum close to the vomer and nasal bones. It forwards chemical signals (such as pheromones) to the central nervous system, thus influencing reproductive and social behavior. In humans, most of its structures except the vomeronasal duct undergo regression after birth. Vomeronasal nerve
Trachea (vertebrates) https://lod.nal.usda.gov/nalt/61127 NA NA
Bronchioles https://lod.nal.usda.gov/nalt/266347 The small airways branching off the tertiary bronchi. Terminal bronchioles lead into several orders of respiratory bronchioles which in turn lead into alveolar ducts and then into pulmonary alveoli. NA
Respiratory mucosa https://lod.nal.usda.gov/nalt/202662 The mucous membrane lining the respiratory tract, including the nasal cavity; the larynx; the trachea; and the bronchi tree. The respiratory mucosa consists of various types of epithelial cells ranging from ciliated columnar to simple squamous, mucous goblet cells, and glands containing both mucous and serous cells. Respiratory epithelium
Gills https://lod.nal.usda.gov/nalt/9339 NA NA
Pleura https://lod.nal.usda.gov/nalt/58808 NA NA
Tracheae (invertebrates) https://lod.nal.usda.gov/nalt/61128 NA NA
Swim bladder https://lod.nal.usda.gov/nalt/61126 NA Swimbladder
Swim bladder https://lod.nal.usda.gov/nalt/61126 NA Gas bladder
Swim bladder https://lod.nal.usda.gov/nalt/61126 NA Air bladder
Topography NALT_URI Definition_NALT Alternative_name
Wounds and injuries https://lod.nal.usda.gov/nalt/728 NA NA
Claws https://lod.nal.usda.gov/nalt/26735 NA Talons
Claws https://lod.nal.usda.gov/nalt/26735 NA Nails (non-primates)
Claws https://lod.nal.usda.gov/nalt/26735 NA Claw horn
Skin (animal) https://lod.nal.usda.gov/nalt/32499 NA NA
Fur https://lod.nal.usda.gov/nalt/27376 NA Coat (animal)
Integument https://lod.nal.usda.gov/nalt/9103 NA Exuviae
Integument https://lod.nal.usda.gov/nalt/9103 NA Body wall
Hairs https://lod.nal.usda.gov/nalt/44301 NA Scalp hair
Hairs https://lod.nal.usda.gov/nalt/44301 NA Hairs (animal)
Antlers https://lod.nal.usda.gov/nalt/10565 NA NA
Hooves https://lod.nal.usda.gov/nalt/45820 NA Hoofs
Sebaceous glands https://lod.nal.usda.gov/nalt/38913 NA Tarsal glands
Wattles https://lod.nal.usda.gov/nalt/47472 NA NA
Scent glands https://lod.nal.usda.gov/nalt/59050 NA Poll glands
Perineum https://lod.nal.usda.gov/nalt/57466 NA NA
Sweat glands https://lod.nal.usda.gov/nalt/38914 NA NA
Insect cuticle https://lod.nal.usda.gov/nalt/9104 NA NA
Scales (integument) https://lod.nal.usda.gov/nalt/47470 NA NA
Comb (integument) https://lod.nal.usda.gov/nalt/28099 NA NA
Feathers https://lod.nal.usda.gov/nalt/34442 NA NA
Nails (integument) https://lod.nal.usda.gov/nalt/47469 NA Nails (primates)
Nails (integument) https://lod.nal.usda.gov/nalt/47469 NA Nails (human)
Esophagus and Gastrointestinal System
Topography NALT_URI Definition_NALT Alternative_name
Esophagus https://lod.nal.usda.gov/nalt/33554 NA Oesophagus
Hepatopancreas https://lod.nal.usda.gov/nalt/9342 NA NA
Intestines https://lod.nal.usda.gov/nalt/42441 NA Intestinal tract
Nasopharynx https://lod.nal.usda.gov/nalt/54355 NA Rhinopharynx
Nasopharynx https://lod.nal.usda.gov/nalt/54355 NA Nasopharynges
Gastric mucosa https://lod.nal.usda.gov/nalt/22390 Lining of the stomach, consisting of an inner epithelium, a middle lamina propria, and an outer muscularis mucosae. The surface cells produce mucus that protects the stomach from attack by digestive acid and enzymes. When the epithelium invaginates into the lamina propria at various regions of the stomach, different tubular gastric glands are formed. These glands consist of cells that secrete mucus, enzymes, hydrochloric acid, or hormones. Gastric glands
Gastric mucosa https://lod.nal.usda.gov/nalt/22390 Lining of the stomach, consisting of an inner epithelium, a middle lamina propria, and an outer muscularis mucosae. The surface cells produce mucus that protects the stomach from attack by digestive acid and enzymes. When the epithelium invaginates into the lamina propria at various regions of the stomach, different tubular gastric glands are formed. These glands consist of cells that secrete mucus, enzymes, hydrochloric acid, or hormones. Cardiac glands
Gastric mucosa https://lod.nal.usda.gov/nalt/22390 Lining of the stomach, consisting of an inner epithelium, a middle lamina propria, and an outer muscularis mucosae. The surface cells produce mucus that protects the stomach from attack by digestive acid and enzymes. When the epithelium invaginates into the lamina propria at various regions of the stomach, different tubular gastric glands are formed. These glands consist of cells that secrete mucus, enzymes, hydrochloric acid, or hormones. Pyloric glands
Gastric mucosa https://lod.nal.usda.gov/nalt/22390 Lining of the stomach, consisting of an inner epithelium, a middle lamina propria, and an outer muscularis mucosae. The surface cells produce mucus that protects the stomach from attack by digestive acid and enzymes. When the epithelium invaginates into the lamina propria at various regions of the stomach, different tubular gastric glands are formed. These glands consist of cells that secrete mucus, enzymes, hydrochloric acid, or hormones. Stomach mucosa
Cloaca https://lod.nal.usda.gov/nalt/26934 NA NA
Large intestine https://lod.nal.usda.gov/nalt/23273 NA NA
Esophageal sphincter https://lod.nal.usda.gov/nalt/38157 NA Oesophagogastric junction
Esophageal sphincter https://lod.nal.usda.gov/nalt/38157 NA Esophagogastric junction
Esophageal sphincter https://lod.nal.usda.gov/nalt/38157 NA Oesophageal sphincter
Liver https://lod.nal.usda.gov/nalt/9344 NA Liver (anatomy)
Ileum https://lod.nal.usda.gov/nalt/46899 NA NA
Colon https://lod.nal.usda.gov/nalt/27880 NA NA
Rectum https://lod.nal.usda.gov/nalt/10589 NA NA
Stomach https://lod.nal.usda.gov/nalt/9350 NA NA
Crop (digestive system) https://lod.nal.usda.gov/nalt/30108 NA Honey sac
Small intestine https://lod.nal.usda.gov/nalt/34888 NA NA
Rumen https://lod.nal.usda.gov/nalt/41231 NA NA
Pancreas https://lod.nal.usda.gov/nalt/2897 NA NA
Anus https://lod.nal.usda.gov/nalt/8441 NA Anal sphincter
Cecum https://lod.nal.usda.gov/nalt/20837 NA Caecum
Gall bladder https://lod.nal.usda.gov/nalt/9338 NA Gallbladder
Omasum https://lod.nal.usda.gov/nalt/41229 NA NA
Duodenum https://lod.nal.usda.gov/nalt/34887 NA NA
Gizzard https://lod.nal.usda.gov/nalt/33557 NA NA
Gastric fundus https://lod.nal.usda.gov/nalt/42409 NA Stomach fundus
Reticulum https://lod.nal.usda.gov/nalt/41230 NA NA
Pharynx https://lod.nal.usda.gov/nalt/33561 NA Pharynges
Oropharynx https://lod.nal.usda.gov/nalt/234524 The middle portion of the pharynx that lies posterior to the mouth, inferior to the soft palate, and superior to the base of the tongue and epiglottis. It has a digestive function as food passes from the mouth into the oropharynx before entering esophagus. NA
Abomasum https://lod.nal.usda.gov/nalt/1770 NA NA
Jejunum https://lod.nal.usda.gov/nalt/48097 NA NA
Pylorus https://lod.nal.usda.gov/nalt/60608 NA NA
Proventriculus https://lod.nal.usda.gov/nalt/33562 NA NA
Urinary System
Topography NALT_URI Definition_NALT Alternative_name
Ureter https://lod.nal.usda.gov/nalt/66771 NA NA
Urethra https://lod.nal.usda.gov/nalt/66772 NA NA
Kidneys https://lod.nal.usda.gov/nalt/9343 NA Head kidney
Kidneys https://lod.nal.usda.gov/nalt/9343 NA Anterior kidney
Bladder https://lod.nal.usda.gov/nalt/17878 A musculomembranous sac along the urinary tract. Urine flows from the kidneys into the bladder via the ureters (ureter), and is held there until urination. Urinary bladder
Urinary tract https://lod.nal.usda.gov/nalt/17881 NA NA
Reproductive System
Topography NALT_URI Definition_NALT Alternative_name
Spermatic cord https://lod.nal.usda.gov/nalt/51286 NA NA
Animal ovaries https://lod.nal.usda.gov/nalt/29278 NA Mammalian ovary
Oviductal ampulla https://lod.nal.usda.gov/nalt/8132 NA NA
Cervix https://lod.nal.usda.gov/nalt/24102 NA Cervix uteri
Cervix https://lod.nal.usda.gov/nalt/24102 NA Uterine cervix
Cloaca https://lod.nal.usda.gov/nalt/26934 NA NA
Epididymis https://lod.nal.usda.gov/nalt/22094 NA NA
Caput epididymidis https://lod.nal.usda.gov/nalt/22093 NA NA
Gynoecium https://lod.nal.usda.gov/nalt/22619 A collective term for the female reproductive structures of a flower. NA
Ovipositor https://lod.nal.usda.gov/nalt/39793 NA NA
Uterine tissue https://lod.nal.usda.gov/nalt/9538 NA NA
Uterus https://lod.nal.usda.gov/nalt/39795 NA NA
Seminiferous tubules https://lod.nal.usda.gov/nalt/62834 NA NA
Prostate gland https://lod.nal.usda.gov/nalt/38912 NA NA
Oviducts https://lod.nal.usda.gov/nalt/39792 Ducts that serve exclusively for the passage of eggs from the ovaries to the exterior of the body. In non-mammals, they are termed oviducts. In mammals, they are highly specialized and known as fallopian tubes. NA
Rete testis https://lod.nal.usda.gov/nalt/61147 NA NA
Prepuce https://lod.nal.usda.gov/nalt/57285 NA NA
Shell gland https://lod.nal.usda.gov/nalt/9347 The specialized glandular part of the oviduct that forms the egg's shell. Egg shell gland
Shell gland https://lod.nal.usda.gov/nalt/9347 The specialized glandular part of the oviduct that forms the egg's shell. Eggshell gland
Scrotum https://lod.nal.usda.gov/nalt/51285 NA NA
Cervical mucus https://lod.nal.usda.gov/nalt/24105 NA NA
Myometrium https://lod.nal.usda.gov/nalt/54164 NA NA
Bulbourethral gland https://lod.nal.usda.gov/nalt/20331 NA Bulbo-urethral gland
Oviductal isthmus https://lod.nal.usda.gov/nalt/47917 NA NA
Ovarian follicles https://lod.nal.usda.gov/nalt/30722 NA Subordinate follicles
Ovarian follicles https://lod.nal.usda.gov/nalt/30722 NA Dominant follicles
Vaginal mucosa https://lod.nal.usda.gov/nalt/53592 NA NA
Testes https://lod.nal.usda.gov/nalt/43422 NA Testicles
Testes https://lod.nal.usda.gov/nalt/43422 NA Testis
Embryo sac https://lod.nal.usda.gov/nalt/36821 NA NA
Accessory sex glands https://lod.nal.usda.gov/nalt/2139 NA Accessory sex organs
Accessory sex glands https://lod.nal.usda.gov/nalt/2139 NA Male ampulla
Accessory sex glands https://lod.nal.usda.gov/nalt/2139 NA Ampulla (male)
Inferior ovary https://lod.nal.usda.gov/nalt/333770 An inferior ovary is one that is situated entirely below the point of attachment of the other floral parts in a flower. NA
Endometrium https://lod.nal.usda.gov/nalt/37037 NA NA
Cauda epididymidis https://lod.nal.usda.gov/nalt/23129 NA NA
Ductus deferens https://lod.nal.usda.gov/nalt/34844 The excretory duct of the testes that carries spermatozoa. It rises from the scrotum and joins the seminal vesicles to form the ejaculatory duct. NA
Penis https://lod.nal.usda.gov/nalt/51284 NA NA
Fallopian tubes https://lod.nal.usda.gov/nalt/188598 A pair of highly specialized muscular canals extending from the uterus to its corresponding ovary. They provide the means for ovum collection, and the site for the final maturation of gametes and fertilization. Uterine tubes
Fallopian tubes https://lod.nal.usda.gov/nalt/188598 A pair of highly specialized muscular canals extending from the uterus to its corresponding ovary. They provide the means for ovum collection, and the site for the final maturation of gametes and fertilization. Salpinges
Fallopian tubes https://lod.nal.usda.gov/nalt/188598 A pair of highly specialized muscular canals extending from the uterus to its corresponding ovary. They provide the means for ovum collection, and the site for the final maturation of gametes and fertilization. Mammalian oviducts
Superior ovary https://lod.nal.usda.gov/nalt/333769 A superior ovary is one that is situated entirely above the point of attachment of the other floral parts in a flower. NA
Vagina https://lod.nal.usda.gov/nalt/39796 NA NA
Seminal vesicles https://lod.nal.usda.gov/nalt/2142 NA Vesicular gland
Corpus epididymidis https://lod.nal.usda.gov/nalt/29276 NA NA
Vulva https://lod.nal.usda.gov/nalt/39797 NA NA
Lymphatic System
Topography NALT_URI Definition_NALT Alternative_name
Spleen https://lod.nal.usda.gov/nalt/9348 NA NA
Peyer's patches https://lod.nal.usda.gov/nalt/50921 Lymphoid tissue on the mucosa of the small intestine. Peyer patches
Adenoids https://lod.nal.usda.gov/nalt/240180 A collection of lymphoid nodules on the posterior wall and roof of the nasopharynx. Pharyngeal tonsils
Bursa of fabricius https://lod.nal.usda.gov/nalt/20540 NA Bursa fabricii
Lymph nodes https://lod.nal.usda.gov/nalt/50915 NA Lymphnodes
Thymus gland https://lod.nal.usda.gov/nalt/37012 NA NA
Tonsils https://lod.nal.usda.gov/nalt/9351 A round-to-oval mass of lymphoid tissue embedded in the lateral wall of the pharynx. There is one on each side of the oropharynx in the fauces between the anterior and posterior pillars of the soft palate. Palatine tonsils
Lymph https://lod.nal.usda.gov/nalt/18343 NA NA
Thoracic duct https://lod.nal.usda.gov/nalt/50922 NA NA
Endocrine System
Topography NALT_URI Definition_NALT Alternative_name
Posterior pituitary https://lod.nal.usda.gov/nalt/54725 Neural tissue of the pituitary gland, also known as the neurohypophysis. It consists of the distal axons of neurons that produce vasopressin and oxytocinin in the supraoptic nucleus and the paraventricular nucleus. These axons travel down through the median eminence, the hypothalamic infundibulum of the pituitary stalk, to the posterior lobe of the pituitary gland. Neurohypophysis
Posterior pituitary https://lod.nal.usda.gov/nalt/54725 Neural tissue of the pituitary gland, also known as the neurohypophysis. It consists of the distal axons of neurons that produce vasopressin and oxytocinin in the supraoptic nucleus and the paraventricular nucleus. These axons travel down through the median eminence, the hypothalamic infundibulum of the pituitary stalk, to the posterior lobe of the pituitary gland. Posterior pituitary gland
Posterior pituitary https://lod.nal.usda.gov/nalt/54725 Neural tissue of the pituitary gland, also known as the neurohypophysis. It consists of the distal axons of neurons that produce vasopressin and oxytocinin in the supraoptic nucleus and the paraventricular nucleus. These axons travel down through the median eminence, the hypothalamic infundibulum of the pituitary stalk, to the posterior lobe of the pituitary gland. Infundibular stalk
Thyroid gland https://lod.nal.usda.gov/nalt/37013 NA Thyroid (gland)
Parathyroid glands https://lod.nal.usda.gov/nalt/37009 NA NA
Pituitary gland https://lod.nal.usda.gov/nalt/9900 A small, unpaired gland situated in the sella turcica tissue. It is connected to the hypothalamus by a short stalk. Hypophysis
Adrenal cortex https://lod.nal.usda.gov/nalt/4339 NA Zona fasciculata
Adrenal cortex https://lod.nal.usda.gov/nalt/4339 NA Zona reticularis
Adrenal cortex https://lod.nal.usda.gov/nalt/4339 NA Zona glomerulosa
Thymus gland https://lod.nal.usda.gov/nalt/37012 NA NA
Endocrine glands https://lod.nal.usda.gov/nalt/4351 Ductless glands that secrete hormones directly into the blood circulation. These hormones influence the metabolism and other functions of cells in the body. NA
Adrenal glands https://lod.nal.usda.gov/nalt/4343 NA NA
Adrenal medulla https://lod.nal.usda.gov/nalt/4352 NA NA
Anterior pituitary https://lod.nal.usda.gov/nalt/4132 The anterior glandular lobe of the pituitary gland, also known as the adenohypophysis. It secretes the adenohypophyseal hormones that regulate vital functions such as growth; metabolism; and reproduction. Adenohypophysis
Anterior pituitary https://lod.nal.usda.gov/nalt/4132 The anterior glandular lobe of the pituitary gland, also known as the adenohypophysis. It secretes the adenohypophyseal hormones that regulate vital functions such as growth; metabolism; and reproduction. Anterior pituitary gland
Nervous System
Topography NALT_URI Definition_NALT Alternative_name
Ganglia https://lod.nal.usda.gov/nalt/1617 NA Ganglion
Cerebrospinal fluid https://lod.nal.usda.gov/nalt/18339 NA NA
Optic lobe https://lod.nal.usda.gov/nalt/19228 NA NA
Meninges https://lod.nal.usda.gov/nalt/23678 NA NA
Mesencephalon https://lod.nal.usda.gov/nalt/334166 The middle of the three primitive cerebral vesicles of the embryonic brain. without further subdivision, midbrain develops into a short, constricted portion connecting the pons and the diencephalon. midbrain contains two major parts, the dorsal tectum mesencephali and the ventral tegmentum mesencephali, housing components of auditory, visual, and other sensorimoter systems. NA
Optic tectum https://lod.nal.usda.gov/nalt/334171 The anterior pair of the quadrigeminal bodies which coordinate the general behavioral orienting responses to visual stimuli, such as whole-body turning, and reaching. Anterior colliculus
Optic tectum https://lod.nal.usda.gov/nalt/334171 The anterior pair of the quadrigeminal bodies which coordinate the general behavioral orienting responses to visual stimuli, such as whole-body turning, and reaching. Superior colliculi
Optic tectum https://lod.nal.usda.gov/nalt/334171 The anterior pair of the quadrigeminal bodies which coordinate the general behavioral orienting responses to visual stimuli, such as whole-body turning, and reaching. Superior colliculus
Hippocampus https://lod.nal.usda.gov/nalt/19223 A curved elevation of gray matter extending the entire length of the floor of the temporal horn of the lateral ventricle. Ammon's horn
Hippocampus https://lod.nal.usda.gov/nalt/19223 A curved elevation of gray matter extending the entire length of the floor of the temporal horn of the lateral ventricle. Hippocampal formation
Amygdala https://lod.nal.usda.gov/nalt/8210 Almond-shaped group of basal nuclei anterior to the inferior horn of the lateral ventricle of the temporal lobe. The amygdala is part of the limbic system. Archistriatum
Amygdala https://lod.nal.usda.gov/nalt/8210 Almond-shaped group of basal nuclei anterior to the inferior horn of the lateral ventricle of the temporal lobe. The amygdala is part of the limbic system. Massa intercalata
Amygdala https://lod.nal.usda.gov/nalt/8210 Almond-shaped group of basal nuclei anterior to the inferior horn of the lateral ventricle of the temporal lobe. The amygdala is part of the limbic system. Amygdaloid nuclear complex
Amygdala https://lod.nal.usda.gov/nalt/8210 Almond-shaped group of basal nuclei anterior to the inferior horn of the lateral ventricle of the temporal lobe. The amygdala is part of the limbic system. Corpus amygdaloideum
Amygdala https://lod.nal.usda.gov/nalt/8210 Almond-shaped group of basal nuclei anterior to the inferior horn of the lateral ventricle of the temporal lobe. The amygdala is part of the limbic system. Intercalated amygdaloid nuclei
Amygdala https://lod.nal.usda.gov/nalt/8210 Almond-shaped group of basal nuclei anterior to the inferior horn of the lateral ventricle of the temporal lobe. The amygdala is part of the limbic system. Amygdaloid body
Amygdala https://lod.nal.usda.gov/nalt/8210 Almond-shaped group of basal nuclei anterior to the inferior horn of the lateral ventricle of the temporal lobe. The amygdala is part of the limbic system. Nucleus amygdalae
Spinal cord https://lod.nal.usda.gov/nalt/23679 NA NA
Cerebellum https://lod.nal.usda.gov/nalt/8211 NA NA
Cerebral cortex https://lod.nal.usda.gov/nalt/24050 NA NA
Thalamus https://lod.nal.usda.gov/nalt/19229 Paired bodies containing mostly gray substance and forming part of the lateral wall of the third ventricle of the brain. The thalamus represents the major portion of the diencephalon and is commonly divided into cellular aggregates known as nuclear groups. NA
Brain https://lod.nal.usda.gov/nalt/9337 NA Forebrain
Brain https://lod.nal.usda.gov/nalt/9337 NA Midbrain
Brain https://lod.nal.usda.gov/nalt/9337 NA Protocerebrum
Brain https://lod.nal.usda.gov/nalt/9337 NA Tritocerebrum
Brain https://lod.nal.usda.gov/nalt/9337 NA Deutocerebrum
Brain https://lod.nal.usda.gov/nalt/9337 NA Hindbrain
Thoracic ganglia https://lod.nal.usda.gov/nalt/42317 NA Thoracic ganglion
Ependyma https://lod.nal.usda.gov/nalt/79494 A thin membrane that lines the ventricles of the brain and the central canal of the spinal cord. NA
Hypothalamus https://lod.nal.usda.gov/nalt/19224 NA NA
Brain stem https://lod.nal.usda.gov/nalt/19221 The part of the brain that connects the cerebral hemispheres with the spinal cord. It consists of the mesencephalon; pons; and medulla oblongata. Locus coeruleus
Brain stem https://lod.nal.usda.gov/nalt/19221 The part of the brain that connects the cerebral hemispheres with the spinal cord. It consists of the mesencephalon; pons; and medulla oblongata. Brainstem
Brain stem https://lod.nal.usda.gov/nalt/19221 The part of the brain that connects the cerebral hemispheres with the spinal cord. It consists of the mesencephalon; pons; and medulla oblongata. Truncus cerebri
Medulla oblongata https://lod.nal.usda.gov/nalt/19225 NA NA
Neocortex https://lod.nal.usda.gov/nalt/199435 NA NA
Abdominal ganglia https://lod.nal.usda.gov/nalt/1615 NA Abdominal ganglion
Subesophageal ganglia https://lod.nal.usda.gov/nalt/42316 NA NA
Cerebrum https://lod.nal.usda.gov/nalt/19222 NA NA
Frontal lobe https://lod.nal.usda.gov/nalt/286312 NA Frontal cortex
Motor cortex https://lod.nal.usda.gov/nalt/281208 NA NA
Preoptic area https://lod.nal.usda.gov/nalt/46761 NA NA
Paraventricular hypothalamic nucleus https://lod.nal.usda.gov/nalt/46760 NA Paraventricular nucleus of the hypothalamus
Cerebral ventricles https://lod.nal.usda.gov/nalt/24054 NA NA
Prefrontal cortex https://lod.nal.usda.gov/nalt/286315 NA Orbital cortex
Prefrontal cortex https://lod.nal.usda.gov/nalt/286315 NA Orbitofrontal cortex
Olfactory bulb https://lod.nal.usda.gov/nalt/19227 NA NA

Arthropod Source

An Arthropod Source is a site where arthropods exist and can be taken (e.g., a water fountain with mosquito larvae). An Arthropod Source can be observed, interpreted, and provide Specimens. An Arthropod Source cannot be diagnosed, shipped, or stored.

Figure 11: Detailed relationships of Arthropod Source in the data model.

If the interest of the Surveillance Activity is at the individual arthropod level (e.g., butterflies with problems in their wings or with parasites), then the user should consider these arthropods as Animal Sources. Arthropods from Animals Sources (attached ticks, lice, fleas, mites) are Specimens (see “Specimens”) from those Animal Source and not Arthropod Sources.

Arthropod Source Record

An Arthropod Source Record represents the set of arthropods collected from an Arthropod Source at time t . For example, mosquitoes captured using a CO₂ trap.

Key attributes of a Arthropod Source Record include:

  • Arthropod Source ID
  • Record Number
  • Number of individuals (full individual, head, thorax, or abdomen) by species, development stage, sex, and condition (for females only).

Other attributes are provided in the Data Dictionary (under construction)

A key characteristic of an Arthropods Source Record is that there can be several species under the Source Record level. For example, mosquitoes collected from a specific site (Source) will be identified and counted by species in the Arthropod Source Record.

When arthropods are collected without effort (No Effort), for example, opportunistically using a brine shrimp net, then the collection method is reported at the Arthropod Source Record level. When the collection implies an effort, the methodology can be inferred from the Point Collection.

Environmental Source

An Environmental Source is a site where measurements on environmental properties can be made or samples can be collected from. An Environmental Source can be observed, tested, and provide abiotic or biotic Specimens. An Environmental Source cannot be shipped or stored.

Figure 12: Detailed relationships of Environmental Source in the data model.

Environmental Source Record

An Environmental Source Record is a site where measurements on environmental properties are made or samples are collected at time t. Many types of samples can be obtained from a Environmental Source Record, for example, feces (with unknown animal origin), water, sediment, and air.

Diagnostics can be conducted on site without requiring the retrieval of specimens and, therefore, they apply to the Environmental Source Record directly. For example, measuring the turbidity of the water at the Environmental Source at time t. The type of substratum used for these direct Diagnostics (e.g., water, air, etc) must be provided.

Key attributes of a Environmental Source Record include:

  • Environmental Source ID
  • Record Number
  • Environmental type

Other attributes are provided in the Data Dictionary (under construction)

Specimen

Figure 13: Position of Specimens in the data model.

Generalities

In the data model, a Specimen refer to a sample collected to conduct Diagnostics (see “Diagnostics”).

Specimens originate from the following:

  • Sampled Group Source Record (e.g., urine collected under a bat roost and the urine cannot be linked to a specific individual of the roost) and Animal Source Records (e.g., an oral swab from an individual animal). These Specimens may consist of either a single sample type (e.g., blood) or multiple tissue types (e.g., mixed blood and saliva).

  • Pools of arthropods comprised of the arthropods present at an Arthropod Source Record.

  • Samples collected from the environment with abiotic origin (e.g., water) or biotic origin (e.g., feces found in the field)

Key attributes of a Specimen include:

  • Specimen ID
  • Type
  • Specimen Original Amount
  • Specimen Current Quantity Stored
  • Origin
  • Ownership

Other attributes are provided in the Data Dictionary (under construction)

Specimens can be stored, and their storage may change multiple times as they are transferred within and between facilities. Similarly, Specimens can be shipped multiple times.

Specimens without any amount of tissue left remain in HAWK so the last Storage, Shipment, and use in Diagnostics can be traced.

Pooled Specimens (under construction)

Specimens in Containers

In situations where space or materials are limited, it is possible that multiple Specimens are stored in a unique container. This approach is clearly not ideal because it can lead to cross-contamination and make actual Specimen tracing more complex. However, the data model has a Container Identifier as a Specimen property (see Data Dictionary). Specific properties for each individual Specimen within the container, such as type, quantity, etc, should allow their visual identification within the container.

Diagnostic

Figure 14: Position of Diagnostic in the data model.

Diagnostics in the data model encompass various methods used to measure health targets of biological, chemical, physical or physiological nature in either Records of Animal, Group, and Environmental Sources or Specimens obtained from Source Records of any type. Diagnostics can range from the clinical examination of an Animal Source to advanced techniques such as metagenomics to sequence nucleic acids present in a Specimen.

Diagnostics report the type and name of the diagnostic method used and who conducted the diagnostic. The actual outcome of a Diagnostic is recorded as a Result (see “Results” below). A single Diagnostic can detect one or multiple targets; therefore, each Diagnostic can have more than one Result.

Key attributes of a Diagnostic include:

  • Diagnostic Method
  • Diagnostic Name
  • Laboratory
  • Date Conducted

Other attributes are provided in the Data Dictionary (under construction)

In the data model, Diagnostics can be conducted in a Laboratory or similar (see Laboratory below) but it is also possible to include field-based assays.

Anomalies in a Group Source Record or Animal Source Record detected through observation or smell (e.g., missing an ear) are not recorded through a Diagnostic but as characteristics of the Group Source Record or Animal Source Record. Similarly, abnormal findings at a specific site detected through observation, smell, or hearing (e.g., smoke) are not recorded through a Diagnostic but they are a property of the Event.

Result

Figure 15: Position of Result in the data model.

A Result request information on the Diagnostic outcome for a single target, in quantitative or qualitative units. A Result can be more specific, reporting the outcome with respect to a gene of a specific pathogen that the Diagnostic can detect. For example, a real-time PCR can target the detection of Influenza A nucleic acid by the amplification of genes X and Z. The Result reports the Ct value for the amplification of either gene X or Z of Influenza A viruses.

Key attributes of a Result include:

  • Target Name
  • Unit
  • Result
  • Interpretation

Other attributes are provided in the Data Dictionary (under construction)

The Result of a Diagnostic can be interpreted as positive, negative, or undetermined, based on the case definition for the parent diagnostic test (reported in the Surveillance Activity metadata).

Storage

A Storage indicates the facility where carcasses of Group Source Records, the carcass of an Animal Source or Specimens are stored. The storage position can be as specific as the exact row of a cryo box in which a vial containing a Specimen is located.

Key attributes of a Storage include:

  • Quantity stored
  • Quantity unit
  • Storage type
  • Facility
  • Building
  • Room
  • Storage Unit
  • Storage problems

Other attributes are provided in the Data Dictionary (under construction)

Multiple Storage units can be added for each Source or Specimen. In the case of Specimens, the recorded Storage units allow to track the current amount available versus the original amount and the reason of the differences over time.

Shipment

A Shipment indicates the movement of carcasses of Group Source Records, the carcass of an Animal Source or Specimens across facilities.

Key attributes of a Shipment include:

  • Quantity shipped
  • Quantity unit
  • Origin
  • Destination
  • Storage method during shipment
  • Status

Other attributes are provided in the Data Dictionary (under construction)

Interpretation

Interpretation of Specimens

In the data model, a Specimen can receive an Interpretation with respect to the hazards targeted in the corresponding Surveillance Activity based on a case definition for a positive, negative, or undetermined Specimen provided in the Surveillance Activity metadata. The Interpretation follows the Results from the Diagnostics conducted using the Specimen and their interpretations.

Specimens can receive multiple Interpretations if they are used in several Diagnostics targeting different hazards.

NoteCase Study 12

The presence of a single target (e.g., SARS-CoV-2) is assessed in a Specimen using three different Diagnostics. The first and second Diagnostic are positive, whilst the Result for the third Diagnostic is negative. Based on these mixed Results, the SARS-CoV-2 status of the Specimen must be interpreted (positive, negative, inconclusive).

Interpretation of Source Records

In the data model, a Source Record can receive an Interpretation with respect to the hazards targeted in the corresponding Surveillance Activity based on a case definition for a positive, negative, or undetermined Source Record provided in the Surveillance Activity metadata. An Interpretation for a Source Record depends on the field findings, Interpretations for the Specimens of the corresponding Source Record, Results of Diagnostics conducted with the Source Records (for Group Source Records and Animal Source Records) and Necropsy findings (for Animal Source Records).

A Source Record can receive multiple Interpretations depending on the hazards targeted.

NoteCase Study 13

The presence of a single target (e.g., Foot and mouth disease virus) is assessed in an Animal Source Record using three different Diagnostics completed with one Specimen and the results of a Necropsy. The Results for the first and second Diagnostic are positive, whilst the Result for the third Diagnostic is negative. The Interpretation for the Specimen is “posiive”. Moreover, the Necropsy do not reveal any important lesions. Based on these Results, the Foot and mouth disease virus status of the Animal Source Record must be interpreted (positive, negative, inconclusive).

Key attributes of a Interpretation include:

  • Quantity shipped
  • Quantity unit
  • Origin
  • Destination
  • Storage method during shipment
  • Status

Other attributes are provided in the Data Dictionary (under construction)

Complexities

Tagging Units

The structure of the data model could be enough to record the hierarchical data. For example, rangers collecting information during patrols (Tracks Effort) in Protected Areas (Locations) at specific points (Events) where dead animals (Source Records) are found at any given time t.

However, the data in another Surveillance Activity with animal captures could have the following data structure:

  • Visit (Field Visit)
    • Protected area (Location),
      • Zones within protected area (Spatial cluster level 1),
        • Grid cells within each zone (Spatial cluster level 2),
          • Capture site (Event)
            • Mist nets at the capture site (Point Effort),
              • Bats captured (Source Records)

Looking at the examples above, the units Location, Event, and Effort might not be enough to accommodate the data structure of certain designs. To solve this limitation, the data model allows to tag units (from Surveillance Activities up to Diagnosis) with labels that allow to further group them in different categories.

NoteCase Study 14

The following example shows a potential data structure for the sampling of animals in markets:

  • Visit (Field Visit)
    • City (Spatial cluster level 1)
      • Neighborhood (Spatial cluster level 2)
        • Market (Location)
          • Vendor (Spatial cluster level 3)
            • Stalls (Spatial cluster level 4)
              • Sampling of animals in a cage (Event)
                • Animal sampled (Source Records)
                  • Rectal Swab (Specimens)

In this case, tagging Events with the corresponding stall id and with the corresponding vendor id will group them by stall and vendor. Locations can be tagged with the corresponding neighborhood and city.

Tags can group units spatially, temporally, or in another way. Tags can be nested, non-nested, or a combination of both.

Unavoidably, the number of Tags, what Tags represent, what they group, the number of categories per group will vary among Surveillance Activities. Therefore, Tag properties must be reported in the Surveillance Activity metadata. In the data model, the only default property for each Tags are the name and the type.

Units Belong to more than One Surveillance Activity

Field Visits, Locations, Events, Sources, Source Records, Specimens, and Diagnostics usually belong to a single Surveillance Activity. This is the Surveillance Activity that lead to generate these data, creating Events, Sources, and Specimens.

However, units can belong to more than one Surveillance Activity:

  • When a Surveillance Activity uses stored carcasses to test them for cardiomegaly and the carcasses were obtained through a previous Surveillance Activity

  • When a Surveillance Activity uses stored specimens to test them for a health target an the carcasses were obtained through a previous Surveillance Activity

NoteCase Study 15

An agency decides to test stored deer samples for SARS-CoV-2. The blood samples have been stored for over a year. The current surveillance initiative is only recycling the samples already collected, its funding source is different, and its objectives and methods are different

In the data model, a new Surveillance Activity is created documenting the new methods and objectives. Then, the Source Records or Specimens to be reused and their parent Field Visits, Locations, Efforts, and Events are added to this new Surveillance Activity. The exception is a field for Field Visit that request its origin. The Field Activity in the original Surveillance Activity has this field completed with “Current Surveillance Activity” whilst in the new Surveillance Activity it should be completed with “Previous Surveillance Activity”. Moreover, Field Visits with origin as “Previous Surveillance Activity” need to report the original Surveillance Activity ID.

New Necropsy, Specimens, Diagnostic, Result, and Interpretation units can be added under the new Surveillance Activity

Outbreak Investigation

As explained in the section “Surveillance Activity”, an outbreak investigation is a Surveillance Activity. An outbreak can be first detected by rangers patrolling a protected area. Therefore, the Field Visit, Location, Event, and Source Records by the rangers belong to the Ranger Patrol” Surveillance Activity and also to the outbreak investigation Surveillance Activity.